Laser Assisted Hatching is a delicate and precise technique used during certain in vitro fertilization (IVF) procedures to improve the chances of successful embryo implantation. The procedure involves creating a small opening, or “hatch,” in the outer shell of the embryo, known as the zona pellucida, using a focused laser beam.
The Zona Pellucida:
The zona pellucida is a protective layer surrounding the early-stage embryo. Before an embryo can implant in the uterine lining, it must break through this protective barrier. However, in some cases, the zona pellucida can be abnormally thick or hard, making it challenging for the embryo to hatch and attach to the uterine wall.
The Role of Laser Assisted Hatching:
Laser Assisted Hatching helps facilitate the embryo’s hatching process, increasing the likelihood of successful implantation in the uterus. By creating a small opening in the zona pellucida, the embryo can more easily break free from its protective shell, enabling it to attach to the uterine lining and initiate a pregnancy.
When is Laser Assisted Hatching Recommended?
Laser Assisted Hatching may be recommended in the following situations:
- Advanced Maternal Age: As a woman’s age advances, the zona pellucida can become thicker and less pliable, making it harder for the embryo to hatch. LAH can be beneficial for women of advanced maternal age undergoing IVF.
- Previous IVF Failures: If a patient has experienced multiple failed IVF attempts, LAH may be considered to improve the chances of successful embryo implantation in subsequent cycles.
- Thick Zona Pellucida: Some women naturally have a thicker or harder zona pellucida, which can impede embryo hatching. LAH can assist in overcoming this challenge.
- Frozen Embryo Transfer: LAH may be used before the freezing of embryos (cryopreservation) to enhance their potential for successful thawing and implantation during a future frozen embryo transfer (FET) cycle.